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Fig. 6 | Cellular & Molecular Biology Letters

Fig. 6

From: Association of cyclin-dependent kinase inhibitor 2B antisense RNA 1 gene expression and rs2383207 variant with breast cancer risk and survival

Fig. 6

CDKN2B-AS1 expression in normal and cancer states. a lncRNA expression in 27 normal tissues from GTEx Portal showed upregulation of CDKN2B-AS1 in colorectal tissue and salivary glands followed by neurons while being down-regulated in breast tissue. b Expression level of lncRNA in breast cancer tissues with different receptor status. c Subcellular localization of CDKN2B-AS1. d–f Analysis of 8925 breast cancer patients in the TCGA across 16 studies. d Expression level of CDKN2B-AS1 according to the gene copy number. e One hundred forty-six patients (2.1%) had a genetic alteration in the CDKN2B-AS1 gene (44 amplifications and 102 deep deletions). f Patients with altered CDKN2B-AS1 had poor survival

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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