Fig. 6

AKT3 was identified as a target of miR-654-3p. A, B AKT3 level detected by qRT-PCR (A) and western blot (B) in HAECs were treated with or without 50 μg/ml Ox-LDL for 24 h. C The putative binding site between miR-654-3p and AKT3 predicted by StarBase. D Results of dual luciferase reporter assay. E, F AKT level detected by qRT-PCR (E) and Western blot (F) in HAECs transfected with miR-654-3p mimics or miR-NC. **P < 0.01