Fig. 5
From: MiR-501 promotes tumor proliferation and metastasis by targeting HOXD10 in endometrial cancer
miR-501 promotes endometrial cancer cell growth and metastasis via downregulating HOXD10. A Protein levels of HOXD10 after being downregulated using two different siRNAs. B MTT assay showed that downregulation of HOXD10 promotes cell growth in Ishikawa cells. C Effect of HOXD10 downregulation on migration and invasion in endometrial cancer cell lines. D Transwell assay revealed that the migration promoting effect of miR-501 could be rescued by up-regulation of HOXD10. E Up-regulation of miR-501 could promote proliferation of Ishikawa cells and over-expression of HOXD10 could abrogate miR-501 induced cell growth. *p < 0.05; **p < 0.01