Fig. 8
From: LncRNA UCA1 promotes development of gastric cancer via the miR-145/MYO6 axis
miR-145/MYO6 axis regulates cell proliferation and apoptosis of GC cells. A CCK-8 assay showed that MYO6 knockdown or miR-145 mimics inhibited cell proliferation of BGC-823 cells. B CCK-8 assay showed that MYO6 knockdown or miR-145 mimics inhibited cell proliferation of MGC-803 cells. C BGC-823 cells transfected with siMYO6 or miR-145 mimics induced G0/G1/ phase arrest. D Flow cytometry assay showed that MGC-803 cells transfected with siMYO6 or miR-145 mimics had G0/G1 phase arrest. E Flow cytometry assay showed that BGC-823 cells transfected with siUCA1 or miR-145 mimics had a higher apoptotic rate. F Flow cytometry assay verified that UCA1 knockdown in MGC-803 cells by siUCA1 transfection induces apoptosis. *p < 0.05, compared with control cells