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Fig. 1 | Cellular & Molecular Biology Letters

Fig. 1

From: HIF-1α/JMJD1A signaling regulates inflammation and oxidative stress following hyperglycemia and hypoxia-induced vascular cell injury

Fig. 1

Stimulation with high glucose decreases cell survival and increases ROS levels in HUVECs. a Cells treated with various concentrations of glucose (25 or 30 mM) for 6, 12, 24, or 48 h reduced cell viability. High glucose (25 or 30 mM) decreased (b) cell viability in a dose- and time-dependent manner, c increased IL-6, IL-8, ICAM-1, and MCP-1 protein secretion by ELISA, and c increased ROS production compared with control. n = 3; *p < 0.05 and **p < 0.01 vs. control; NG, control

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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