Fig. 6From: Primary high-grade serous ovarian cancer cells are sensitive to senescence induced by carboplatin and paclitaxel in vitroDevelopment of the senescence-associated secretory phenotype (SASP) in DIPS cells. Changes in mRNA of arbitrarily selected targets, as quantified according to RT-qPCR (a). Changes in the secretion of respective proteins into the environment (conditioned medium), as quantified by ELISA (b). The results are based on 6–8 independent experiments using HGSOCs obtained from different patients. The results are expressed as the means ± SEM. *p < 0.05 vs. young cellsBack to article page