Fig. 1From: LAGE3 promoted cell proliferation, migration, and invasion and inhibited cell apoptosis of hepatocellular carcinoma by facilitating the JNK and ERK signaling pathwayLAGE3 was upregulated in HCC and correlated with poor overall survival. A LAGE3 expression in HCC. TPM, transcripts per million. B Overall survival of HCC patients with high LAGE3 expression. HR, hazard ratio. C Expression of LAGE3 mRNA in four HCC cell lines (Huh7, Hep3B, SK-HEP1, and HCC-LM3 cells). D Relative expression of LAGE3 in Hep3B cells transfected with LAGE3-OE. E Effects of four different siRNA sequences targeting LAGE3 on its gene expression in SK-HEP1 cells. F Western blot bands of LAGE3 in Hep3B cells transfected with LAGE3-OE or SK-HEP1 cells transfected with LAGE3 siRNAs. Data are shown as mean ± standard deviation. *p < 0.05, **p < 0.01Back to article page