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Fig. 3 | Cellular & Molecular Biology Letters

Fig. 3

From: SNHG3 could promote prostate cancer progression through reducing methionine dependence of PCa cells

Fig. 3

SNHG3 serves as a molecular sponge of miR-152-3p. A Venn diagram of predicted target miRNAs and differential miRNAs; B heatmap of Pearson correlation analysis of candidate target miRNA and SNHG3; C scatter plot of Pearson correlation analysis of miR-152-3p and SNHG3; D box plot of miR-152-3p level in normal and tumor groups; E Kaplan–Meier survival analysis of overall survival and disease-free survival between miR-152-3p high expression and low expression patients in TCGA database. F Binding sequences of SNHG3 and miR-152-3p; G miR-152-3p level in PCa clinical tissue and paired non-tumor adjacent tissue (normal = 40, tumor = 40); H miR-152-3p expression in PCa cell lines and normal cell line. The experiment was repeated 3 times, *p < 0.05; I dual-luciferase assay validated targeted relationship of miR-152-3p and SNHG3 in Du 145 cells. The experiment was repeated 3 times, *p < 0.05; J RIP assessed the enrichment of miR-152-3p and SNHG3 in Ago2 immunoprecipitation. The experiment was repeated 3 times, *p < 0.05; K miR-152-3p level in Du 145 cells and LNCaP cells with sh-SNHG3 or oe-SNHG3. The experiment was repeated 3 times, *p < 0.05

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