Fig. 5
From: SNHG3 could promote prostate cancer progression through reducing methionine dependence of PCa cells
SNHG3 facilitates growth of PCa cells via miR-152-3p/SLC7A11 axis. A SCL7A11 mRNA expression in cells of each transfection group (sh-NC, sh-SNHG3, sh-SNHG3 + miR-152-3p inhibitor, sh-SNHG3 + oe-SLC7A11), *p < 0.05; B protein expression of SLC7A11 in cells of each transfection group, *p < 0.05; C CCK-8 assayed proliferative ability of Du 145 cells, *p < 0.05; D colony formation assay detected colony formation of Du 145 cells, *p < 0.05; E transwell measured migration and invasion of Du 145 cells, *p < 0.05; F, G flow cytometry assessed apoptosis and cell cycle progress of Du 145 cells. All the above experiments were repeated 3 times, *p < 0.05