Table 1 The association of ROBO1 expression with clinical parameters in HCC patients
Characteristic | Low expression of ROBO1 | High expression of ROBO1 | p |
|---|---|---|---|
n | 187 | 187 | |
Age, n (%) | 0.797 | ||
≤ 60 | 87 (23.3%) | 90 (24.1%) | |
> 60 | 100 (26.8%) | 96 (25.7%) | |
Gender, n (%) | 0.507 | ||
Female | 64 (17.1%) | 57 (15.2%) | |
Male | 123 (32.9%) | 130 (34.8%) | |
Race, n (%) | 0.617 | ||
Asian | 76 (21%) | 84 (23.2%) | |
Black or African American | 10 (2.8%) | 7 (1.9%) | |
White | 94 (26%) | 91 (25.1%) | |
Pathologic stage, n (%) | 0.384 | ||
Stage I | 91 (26%) | 82 (23.4%) | |
Stage II | 40 (11.4%) | 47 (13.4%) | |
Stage III | 36 (10.3%) | 49 (14%) | |
Stage IV | 3 (0.9%) | 2 (0.6%) | |
T stage, n (%) | 0.563 | ||
T1 | 97 (26.1%) | 86 (23.2%) | |
T2 | 44 (11.9%) | 51 (13.7%) | |
T3 | 38 (10.2%) | 42 (11.3%) | |
T4 | 5 (1.3%) | 8 (2.2%) | |
N stage, n (%) | 1.000 | ||
N0 | 124 (48.1%) | 130 (50.4%) | |
N1 | 2 (0.8%) | 2 (0.8%) | |
M stage, n (%) | 1.000 | ||
M0 | 132 (48.5%) | 136 (50%) | |
M1 | 2 (0.7%) | 2 (0.7%) | |
Histologic grade, n (%) | < 0.001 | ||
G1 | 39 (10.6%) | 16 (4.3%) | |
G2 | 95 (25.7%) | 83 (22.5%) | |
G3 | 45 (12.2%) | 79 (21.4%) | |
G4 | 4 (1.1%) | 8 (2.2%) | |
AFP (ng/ml), n (%) | 0.012 | ||
≤ 400 | 123 (43.9%) | 92 (32.9%) | |
> 400 | 25 (8.9%) | 40 (14.3%) | |
Age, median (IQR) | 61 (52, 69) | 61 (51.25, 68) | 0.486 |