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Fig. 5 | Cellular & Molecular Biology Letters

Fig. 5

From: SETD8 cooperates with MZF1 to participate in hyperglycemia-induced endothelial inflammation via elevation of WNT5A levels in diabetic nephropathy

Fig. 5

MZF1 regulates WNT5A expression and inflammatory factors in HGECs. a Western blot analysis of MZF1, p-p65, and WNT5A in HGECs. b–e mRNA expression of MZF1, WNT5A, IL-6, and TNFα in HGECs. f Western blot analysis of MZF1, p-p65, and WNT5A in HGECs. g–j mRNA expression of MZF1, WNT5A, IL-6, and TNFα in HGECs. k MZF1 in promoter region of WNT5A. l Luciferase assays of effect of MZF1 on WNT5A promoter activity (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, n = 5 per group)

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