Fig. 7

In vivo biotoxicity assessment. A–G Blood biochemistry data, including ALB (A), TP (B), LDH (C), ALT (D), AST (E), BUN (F), and CRE (G). H H&E-stained results of liver and kidney. The pathological changes were observed under light microscope with ×100 and ×400 magnification. Red arrow represents inflammatory cells, black arrow represents necrosis, green arrow represents renal tubular epithelial edema cells, yellow arrow represents damaged casts. Each value represents means ± SD (n = 6, *P < 0.05, compared with Con, Vehicle, Bor group; ^#P < 0.05, compared with CDDP group)