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Fig. 7 | Cellular & Molecular Biology Letters

Fig. 7

From: Artemisinin relieves osteoarthritis by activating mitochondrial autophagy through reducing TNFSF11 expression and inhibiting PI3K/AKT/mTOR signaling in cartilage

Fig. 7

Schematic working model. AT suppressed the expression of TNFSF11 and inhibited the PI3K–AKT–mTOR pathway in IL-1β induced OA. In the absence of AT, TNFSF11 activated the PI3K–AKT–mTOR pathway to inhibit autophagy in IL-1β induced OA. In the presence of AT, downregulated TNFSF11 suppressed the PI3K–AKT–mTOR pathway to promote autophagy in IL-1β-induced OA

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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