Fig. 8
From: The O-glycosylating enzyme GALNT2 acts as an oncogenic driver in non-small cell lung cancer
The PI3K/Akt and MAPK/ERK pathways can be regulated by GALNT2 in NSCLC. A Enrichment plots from GSEA. B Heatmap and volcano plot of DEGs. C GO annotation and KEGG analysis of DEGs. D Effects of GALNT2 knockdown on the expression of PI3K/AKT and MAPK/ERK pathways. E CCK-8 assay. F Colony formation assay. G Transwell migration and Matrigel invasion assays (magnification, ×100). OV GALNT2 overexpression lentivirus, shRNA GALNT2 shRNA lentivirus, shNC negative control shRNA lentivirus. *P < 0.05