Tumor type | Expression | Role | Function role | miRNAs | Related genes | References |
---|---|---|---|---|---|---|
Oral squamous cell carcinoma | Upregulation | Oncogene | Proliferation, invasion, and migration | miR-150-5p | GLUT-1 | [9] |
Oral squamous cell carcinoma | Upregulation | Oncogene | Proliferation and chemoresistance | miR-194-5p | HIF1a | [75] |
Esophageal cancer | Upregulation | Oncogene | Proliferation, migration, and invasion | miR-186-5p | PTTG1 | [10] |
Esophageal cancer | Upregulation | Oncogene | Growth and invasion | miR-203 | LASP1 | [78] |
Esophageal cancer | Upregulation | Oncogene | Migration and invasion | miR-145 | FSCN1 | [79] |
Gastric cancer | Upregulation | Oncogene | Growth and invasion | / | FOXM1 | [84] |
Gastric cancer | Upregulation | Oncogene | Angiogenesis | / | Slug/VEGFA | [43] |
Gastric cancer | Upregulation | Oncogene | Growth and invasion | miR-186 | HIF-1α | [85] |
Gastric cancer | Upregulation | Oncogene | Growth and invasion | miR-152 | FGF2/CD151 | [86] |
Gastric cancer | Upregulation | Oncogene | EMT | miR-30a | Snail | [87] |
Liver cancer | Upregulation | Oncogene | Proliferation | / | NOP2 | [92] |
Liver cancer | Upregulation | Oncogene | Growth and invasion | miR-214 | / | [44] |
Liver cancer | Upregulation | Oncogene | Proliferation | / | P53 | [95] |
Liver cancer | Upregulation | Oncogene | Migration and invasion | miR-3619-5p | MKL1 | [97] |
Liver cancer | Upregulation | Oncogene | Invasion and migration | miR-186-5p | YAP1 | [98] |
Liver cancer | Upregulation | Oncogene | Growth and invasion | miR-150 | HIG2 | [99] |
Liver cancer | Upregulation | Oncogene | Proliferation | miR-424-5p | INCENP | [100] |
Liver cancer | Upregulation | Oncogene | Autophagy | miR-365 | ATG3 | [101] |
Cholangiocarcinoma | Upregulation | Oncogene | Proliferation, migration, and invasion | miR-186 | SEMA4D | [14] |
Cholangiocarcinoma | Upregulation | Oncogene | Migration and invasion | / | ANGPTL4 | [45] |
Gallbladder cancer | Upregulation | Oncogene | Proliferation | miR-18b-5p | HIF1A | [13] |
Gallbladder cancer | Upregulation | Oncogene | Proliferation, migration, and invasion | miR-143 | HK2 | [105] |
Gallbladder cancer | Upregulation | Oncogene | Growth and invasion | miR-30d-5p | / | [106] |
Pancreatic cancer | Upregulation | Oncogene | EMT | / | TGF-β/Smad | [108] |
Pancreatic cancer | Upregulation | Oncogene | EMT | / | P21 | [109] |
Pancreatic cancer | Upregulation | Oncogene | Proliferation and migration | miR-448 | SERBP1 | [110] |
Pancreatic cancer | Upregulation | Oncogene | Progression and glycolysis | miR-519d-3p | HIF-1A | [111] |
Pancreatic cancer | Upregulation | Oncogene | Autophagy | miR-20a-5p | ULK1 | [113] |
Pancreatic cancer | Upregulation | Oncogene | Chemoresistance | / | EZH2 | [115] |
Pancreatic cancer | Upregulation | Oncogene | Proliferation | miR-1207 | / | [116] |
Pancreatic cancer | Upregulation | Oncogene | Chemoresistance | miR-409 | SHH/GLI/MGMT | [117] |
Pancreatic cancer | Upregulation | Oncogene | Chemoresistance | miR-619-5p | Pygo2 | [118] |
Pancreatic cancer | Upregulation | Oncogene | Autophagy and chemoresistance | miR-143 | HIF-1α/VMP1 | [119] |
Colorectal cancer | Upregulation | Oncogene | Proliferation and metastasis | miR-26b | / | [11] |
Colorectal cancer | Upregulation | Oncogene | Metastasis | miR-152-3p | VEGFA, EGFR | [125] |
Colorectal cancer | Upregulation | Oncogene | EMT | miR-216a-5p | YBX1 | [126] |
Colorectal cancer | Upregulation | Oncogene | EMT | miR-16-5p | VEGFA | [127] |
Colorectal cancer | Upregulation | Oncogene | EMT | miR-186 | Twist1 | [128] |
Colorectal cancer | Upregulation | Oncogene | Proliferation, invasion, and migration | miR-455 | RAF-1 | [129] |
Colorectal cancer | Upregulation | Oncogene | Growth and invasion | miR-30d-5p | RUNX2 | [130] |
Colorectal cancer | Upregulation | Oncogene | Invasion and growth | miR-214-3p | IRS1 | [131] |
Colorectal cancer | Upregulation | Oncogene | Apoptosis | miR-146a | COX2 | [132] |
Colorectal cancer | Upregulation | Oncogene | Proliferation, migration, and invasion | miR-106b-5p | FJX1 | [133] |
Colorectal cancer | Upregulation | Oncogene | Proliferation | miR-761 | MAPK1 | [134] |