Fig. 3

The effect of SNHG16 on ESCC cell tumourigenesis in vivo. Images of the xenograft model in BALB/c nude mice from four treatment groups (n = 6 for each group) on day 35. A Images of mice and tumour volumes of LV-SNHG16 and the control group (LV-NC). B Tumour volumes and growth curve of KD-SNHG16 and the control group (KD-NC). C Tumour sections under HE staining and IHC staining for Ki-67 and CD34. Scale bar, 100 μm. Data are listed as the mean ± SD of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001