Fig. 4

A β-carotene alleviated the aging of Bm-MSCs. A Sa-β-gal positive cells were decreased under β-carotene treatment. n = 5 biological replicates. B The expression levels of p16/p21/p53 was reduced under β-carotene treatment. C Bm-MSCs proliferation was increased under β-carotene treatment. n = 3 biological replicates. D Cell cycle was changed by β-carotene treatment. E β-carotene treatment reduced the expression of γ-H2A.X and 53BP1 expression