Fig. 8
From: E2F1 promotes cell cycle progression by stabilizing spindle fiber in colorectal cancer cells
E2F1-induced stathmin1 and TACC3 are associated with a poor prognosis in CRC patients. A Immunohistochemical analysis of the levels of E2F1, stathmin1, p-stathmin1, TACC3, p-TACC3, and Ki-67 in pathological CRC tissues (scale bar, 100 μm). Representative images of two CRC patients are shown. B Correlation among concurrent immunostaining scores of E2F1, stathmin1, and TACC3 in CRC tissues. Spearman’s test was used to analyze the correlations. C Overall survival of probability of CRC patients with high (n = 117) and low (n = 114) expression of E2F1, high (n = 114) and low (n = 117) expression of stathmin 1, high (n = 102) and low (n = 129) expression of TACC3, and high (n = 63) and low (n = 68) expression of E2F1/stathmin1/TACC3