Fig. 5
From: Targeting UBR5 in hepatocellular carcinoma cells and precise treatment via echinacoside nanodelivery
AMPG enhances the anticancer effects of ECH in HepG2 cells with UBR5 overexpression. A, B mRNA and protein expression of UBR5 in HepG2 cells transduced with indicated plasmids. C, D Cell apoptosis, E OCR, F ECAR, and G UBR5, LDHA, PKM2, Survivin, C-myc, and β-catenin expression in HepG2 cells transduced with indicated plasmids and incubated with ECH, AMPG, and ECH@AMPG. **P < 0.01, ***P < 0.001 compared with vector. ###P < 0.001 compared with UBR5. ΔΔΔP < 0.001 compared with UBR5 + ECH