Fig. 3
From: MF-094 nanodelivery inhibits oral squamous cell carcinoma by targeting USP30
USP30 promotes c-Myc deubiquitination. A Interaction between USP30 and c-Myc in HSC4 cells. c-Myc expression in B HSC4 and C SCC4 cells with or without USP30 knockdown and overexpression. c-Myc levels in HSC4 cells with USP30 knockdown with or without D protease inhibitor MG132 (10 μM) or E CHX treatment. F Effect of USP30 overexpression on c-Myc ubiquitination in SCC4 cells transfected with WT-USP30, C77S-mutant USP30, or vector. G Effect of USP30 knockdown on c-Myc ubiquitination in HSC4 cells