Fig. 4

A–C SV subtypes identified on the basis of WGS. The distribution of SV subtypes in A ATC (8305C), B PTC (BCPAP), and C PTC (TPC-1) cells. SVs were identified by DELLY2. D Differences in TAD changes between ATC (8305C), PTC (BCPAP and TPC-1), and normal thyroid cell lines. The ratio of short-range to long-range TAD blocks in ATC, PTC, and normal cell-lines. E–G SV breakpoints associated with TAD boundaries. The distribution of SV subtypes across (span-SV) or within nearest TAD boundaries (within-SV) in E ATC (8305C), F PTC (BCPAP), and G PTC (TPC-1) cells