Fig. 6

Effect of CC on the protective role of melatonin pretreatment in septic mice. a Sepsis scores. b Blood biochemical parameters. c Blood routine parameters. d Representative echocardiography images of the long axis. e SV, CO, LVEDV, and LVESV statistical graphs of the long axis. f Representative echocardiography images of the short axis. g SV, CO, LVEDV, and LVESV statistical graphs of the short axis. h Representative western blot protein bands of p-AMPK, AMPK, p-ACC, and ACC in mouse heart tissues. i Quantitative analysis of western blot by normalizing to GAPDH. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 versus sham or versus CLP or MEL + CLP; ns, nonsignificant. n = 6 for each group. Statistical analysis of data was performed using ANOVA