Fig. 2

The effect of intrinsic TGF-β signaling on muscle inflammation and regeneration. A Histological features of the CTX-damaged TA muscle in control or SM TGF-βr2^−/− mice. B Representative immunofluorescence staining results of CD11b, F4/80, and dystrophin in damaged TA muscle. C FACS analysis of the proportion of CD45⁺CD11b⁺ and CD45⁺F4/80⁺  cells sorted from TA muscle on days 4 and 7 post-injury. D, E Embryonic myosin heavy chain (eMHC) staining and the quantitative results in damaged TA muscle. All data are presented as means ± SD (n = 3). One-way ANOVA was used for multiple comparisons (*P < 0.05). Bar = 50 μm