Fig. 9

p-38 MAPk activity relates to TGF-β-IRE1α signaling in inflamed muscle cells. A The protein levels of Erk, Jnk, p38, and p65 in control or SM TGF-βr2^−/− mice-derived MPC-myotubes, with or without stimulation of IFN-γ/LPS, SRI, 4-PBA, and/or 4μ8C, analyzed by Western blot. The relative protein expression values are expressed as a ratio [phosphorylated (P) protein/total (T) protein]. B Immunofluorescence staining and the quantitative results of P-p38 MAPK in damaged TA muscle. All data are presented as means ± SD (n = 3). A one-way ANOVA was used for multiple comparisons (*P < 0.05; **P < 0.01). Bar = 50 μm