Fig. 2

BMECs secrete miR-3613-3p to transfer into microglia via exosomes. A miR-3613-3p expression in BMEC exosome after transfection was detected by RT-qPCR. B HMC3s were treated with PKH 67 fluorescently labeled BMEC exosome, and the fluorescence was observed under a fluorescence microscope. Green, PKH 67 fluorescence. C miR-3613-3p expression in HMC3 after co-culturing with BMEC exosomes was detected by RT-qPCR. Differences were analyzed using ANOVA, followed by post-hoc Dunnett’s multiple comparisons test. *p < 0.05