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Table 2 Relationship between DGKK expression and clinicopathological features of patients with sepsis-induced lung injury

From: Extracellular vesicles derived from CD4+ T cells carry DGKK to promote sepsis-induced lung injury by regulating oxidative stress and inflammation

 

Control subjects

Sepsis

P value

DGKK low

DGKK high

Age

Male, n (%)

BMI (kg/m2)

White cell count (× 109/L)

C-reactive protein (mg/L)

IL-6 (pg/mL)

TNF-α (pg/mL)

SOFA score

History of hypertension, n (%)

History of hyperlipidemia, n (%)

History of diabetes, n (%)

History of CKD, n (%)

History of CCVD, n (%)

History of asthma, n (%)

History of COPD, n (%)

57.9 ± 8.4

13 (65)

25.5 ± 3.0

5.3 ± 1.0

1.5 ± 0.7

16.0 (10.3–16.3)

40.8 (28.6–49.9)

2 (1–3)

11 (55)

12 (60)

8 (40)

9 (45)

12 (60)

12 (60)

10 (50)

59.9 ± 11.8

8 (40)

25.3 ± 3.1

12.7 ± 0.4

138.5 ± 48.7

41.9 (18.7–55.6)

118.0 (90.2–127.2)

4 (3–5)

8 (40)

8 (40)

13 (65)

13 (65)

7 (35)

8 (40)

6 (30)

65.7 ± 10.3

14 (70)

23.4 ± 2.4

14.5 ± 1.13

169.8 ± 40.6

55.9 (37.3–77.2)

126.4 (103.4–149.0)

7 (5–8)

14 (70)

13 (65)

7 (35)

8 (40)

14 (70)

14 (70)

16 (80)

0.060

0.119

0.054

 < 0.001

 < 0.001

 < 0.001

 < 0.001

 < 0.001

0.162

0.243

0.125

0.247

0.072

0.150

0.006

  1. Results expressed as mean ± SD or median (interquartile range)
  2. CKD chronic kidney disease, CCVD cardiovascular and cerebrovascular diseases, COPD chronic obstructive pulmonary disease, SOFA sequential organ failure assessment