Fig. 1
From: The role of noncoding RNAs in metabolic reprogramming of cancer cells
Noncoding RNAs regulate metabolism in cancer cells. MCT1: monocarboxylate transporter 1; GLUT: glucose transporter; ASCT2: alanine, serine, cysteine, and glutamate transporter; IGF1-R: insulin like growth factor1 receptor; G6P: glucose-6-phosphate; PEP: phosphoenolpyruvate; HK2: hexokinase 2; PFKFB2: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2; PKM2: pyruvate kinase isozyme M2; PDH: pyruvate dehydrogenase; PDK1: pyruvate dehydrogenase kinase 1; G6PD: glucose-6-phosphate-dehydrogenase; TKT: transketolase; IRS1: insulin receptor substrate 1; GAA: glutamic acid; GATM: glycine amidinotransferase; Ac-CoA: acetyl-CoA; GOT1: glutamate–oxaloacetate transaminase 1; α-KG: alpha-ketoglutarate; GSH: glutathione; GCLC: glutamate-cysteine arginine ligase catalytic subunit; GLS: glutaminase; MAT1A: methionine adenosyltransferase 1A; CPT1A: carnitine palmitoyltransferase 1A; CROT: carnitine O-octanoyltransferase; HADHB: hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; ABCA1: ATP binding cassette subfamily A member 1; SPHK1: sphingosine kinase 1; TAG: triacylglycerol; DAG: diacylglycerol; G: glycerol; FA: fatty acid; IRS1: insulin receptor substrate 1; Arg: arginine; GAA: glutamic acid; GATM: glycine amidinotransferase; Ac-CoA: acetyl-CoA; GOT1: glutamate–oxaloacetate transaminase 1; GOT2: glutamate–oxaloacetate transaminase 2; α-KG: alpha-ketoglutarate; Asp: aspartate; OAA: oxaloacetate; GLS: glutaminase