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Fig. 4 | Cellular & Molecular Biology Letters

Fig. 4

From: CircRNF10-DHX15 interaction suppressed breast cancer progression by antagonizing DHX15-NF-κB p65 positive feedback loop

Fig. 4

CircRNF10 and DHX15 were involved in the activation of NF-κB signaling pathway. A Western blotting assay showing the expression of p65, p-p65 (S536), and cyclin D1 in BC cells in si-circRNF10 group and control. B Western blotting assay showing the expression of p65, p-p65 (S536), and cyclin D1 in BC cells in LV-circRNF10 group and control. C Western blotting presenting the cytoplasmic and nuclear p65 levels in si-NC group and si-circRNF10 group of BC cells. D Western blotting presenting the cytoplasmic and nuclear p65 levels in LV-vector group and LV-circRNF10 group of BC cells. E IF assay indicating the subcellular localization of p65 in si-NC group and si-circRNF10 group of BC cells. Red: p65, blue: DAPI. F IF assay indicating the subcellular localization of p65 in LV-vector group and LV-circRNF10 group of BC cells. Red: p65, blue: DAPI. G Western blotting analysis showing the influence of si-DHX15 on expression of p65, p-p65 (S536), and cyclin D1 in BC cells. H Western blotting analysis showing the influence of LV-DHX15 on expression of p65, p-p65 (S536), and cyclin D1 in BC cells. I Western blotting analysis presenting the cytoplasmic and nuclear p65 levels in si-NC group and si-DHX15 group of BC cells. J Western blotting analysis presenting the cytoplasmic and nuclear p65 levels in LV-vector group and LV-DHX15 group of BC cells. K IF assay showing the subcellular localization of p65 in si-NC group and si-DHX15 group of BC cells. Red: p65, blue: DAPI. L IF assay showing the subcellular localization of p65 in LV-vector group and LV-DHX15 group of BC cells. Red: p65, blue: DAPI

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