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Fig. 7 | Cellular & Molecular Biology Letters

Fig. 7

From: CircRNF10-DHX15 interaction suppressed breast cancer progression by antagonizing DHX15-NF-κB p65 positive feedback loop

Fig. 7

CircRNF10 suppressed BC growth in vivo. A Photograph of tumors in female BALB/c nude mice injected with LV-vector or LV-circRNF10 MDA-MB-231 cells (N = 5 for each group). B The calculated volume of tumors in LV-vector group and LV-circRNF10 group. C The weight of tumors in LV-vector group and LV-circRNF10 group. D Representative IHC images showing the expression of Ki-67, p65, and DHX15 in tumors of LV-vector group and LV-circRNF10 group. E Schematic illustration showing the mechanism of circRNF10 in inhibiting BC progression. Error bars represent the mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

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