Fig. 4
From: Profiling the impact of the promoters on CRISPR-Cas12a system in human cells
Transcriptional activation ability comparison of the CRISPR-Cas12a systems with different promoters. a Schematic of the gene activation systems based on CRISPR-Cas12a systems with different promoters. VPR, synthetic VP64-p65-Rta activation domain. b–d qPCR analysis of the transcriptional activation among the CRISPR-Cas12a systems with different promoters guided by a single crRNA targeting each promoter region of MYOD (b), IL1RN (c), and HBG (d) in human MCF7 cells. Mean values are presented with SEM, n = 3 independent experiments