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Fig. 5 | Cellular & Molecular Biology Letters

Fig. 5

From: Galectin-1 promotes angiogenesis and chondrogenesis during antler regeneration

Fig. 5

Functional analysis on co-expressed DEGs between the APCGAL-1−/− vs. APCWT and APCGAL-1−/− vs. APCVector. A GO analysis in BP was performed on 392 up-regulated (pink bar) and 771 down-regulated (blue bar) DEGs in APCGAL-1−/−. Y-axis represents the important GO terms (adjusted P < 0.01). B, C KEGG analysis was performed on the 392 up-regulated (B) and 771 down-regulated (C) DEGs in APCGAL-1−/−, respectively. The horizontal axis represents the gene ratio, the percentage of total DEGs in the given KEGG pathways. The bubble size represents the number of DEGs involved. The bubble color key from white to purple indicates low to high -log10 value of adjusted P-values (adjusted P-values < 0.01). D, E Enriched DEGs relating to GO terms on angiogenesis (D) and cell differentiation (E), respectively. The DEGs interaction network is divided into 17 gene clusters. The two main gene clusters were performed. One is an angiogenesis and bone development-related gene cluster (F), and another is an immune response-related gene cluster (G)

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