Fig. 5
From: Notch mediates the glycolytic switch via PI3K/Akt signaling to support embryonic development
Notch signaling mediated glycolysis switch via PI3K/Akt signaling to support goose embryonic development. A–E Effect of in ovo 10 nM DAPT, 60 µM LY294002, or 50 µg/mL 740Y-P injection in the yolk sac on Notch signaling (A–C) and PI3K/Akt signaling (B, D, and E) in the liver of geese embryos (n = 6). B and F–H Lactate content, ATP levels, activities of HK, PFK, and PK (F), and the relative mRNA expressions (G) and protein abundances (B, H) of HK2, PFK, PKM, and LDHA in the liver of embryos in ovo injected with 10 nM DAPT, 60 µM LY294002, or 50 µg/mL 740Y-P in the yolk sac (n = 6)