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Fig. 3 | Cellular & Molecular Biology Letters

Fig. 3

From: A novel tyrosine tRNA-derived fragment, tRFTyr, induces oncogenesis and lactate accumulation in LSCC by interacting with LDHA

Fig. 3

tRFtyr-mediated modulation of LSCC progression in vitro. A DNA synthesis monitored by EdU labelling of the indicated laryngeal cancer cells (tRFTyr-KD and tRFTyr-Con). The red fluorescence signal indicates EdU-positive cells, and the blue fluorescence signal indicates nuclei. B The average relative EdU-positive cell rate was calculated to indicate laryngeal cancer cells. C Growth curves of tRFTyr-KD and tRFtyr-Con cells were generated by a CCK-8 assay. D, E A representative colony formation assay in the indicated LSCC cells was conducted. F, G Transwell assays were conducted to detect the migratory and invasive abilities of the indicated laryngeal cancer cells

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