Fig. 1
From: The role of NPY2R/NFATc1/DYRK1A regulatory axis in sebaceous glands for sebum synthesis
Abundant SG distributed in pubertal skin. A H&E staining show the SG count and size in MS, VS and AS of PND-25 and PND-35 rat (magnification ×100). B IF show the expression of KRT5 and KRT10 in MS and VS of PND-25, PND-35 and PND-35 with SF-11 (magnification ×200). C Oil red O staining show the lipid droplet content in MS, VS and AS of PND-25, PND-35 and PND-35 with SF-11 (magnification ×200). The SG specimens from three individuals were used for immunofluorescence. Ten visual fields were randomly selected to count the positive staining, and calculate the proportion and statistical significance using Student’s t-test. “*” and “#” represent p-value less than 0.05 compared to the prior group. H&E: Hematoxylin and eosin staining; SG: sebaceous gland; PND: post-natal day; MS: mammary skin; VS: volar skin; AS: abdominal skin; IF: immunofluorescence; IP: immunoprecipitation; SF-11: NPY2R antagonist; DYRK1-IN-1/IN: DYRK1A inhibitor; DEGs: differential expressed genes; NFATc1: nuclear factor of activated T cells 1