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Fig. 3 | Cellular & Molecular Biology Letters

Fig. 3

From: EFEMP2 upregulates PD-L1 expression via EGFR/ERK1/2/c-Jun signaling to promote the invasion of ovarian cancer cells

Fig. 3

Effects of up-regulated or down-regulated EFEMP2 on EMT-related gene expression and in vivo growth of subcutaneous grafts. Western blot analysis was performed to detect (a) the effect of down-regulated EFEMP2 on the expression of EMT-related genes, and (b) the influence of EFEMP2 over-expression on the expression of EMT-related genes. c The graph illustrated the growth rate and size of tumors in nude mice after shRNA transfection. d The graph illustrated the growth rate and size of tumors in nude mice after over-expression transfection. e The images of subcutaneous graft tumors after inoculation with ES-2, ES-2 shRNA1, OVCAR-3, or OVCAR-3 EX cells. *p < 0.05, **p < 0.01, or***P < 0.001

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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