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Fig. 2 | Cellular & Molecular Biology Letters

Fig. 2

From: CRISPR/Cas13d targeting GZMA in PARs pathway regulates the function of osteoclasts in chronic apical periodontitis

Fig. 2

GZMA promoted the cell proliferation of osteoclast and inhibited cell apoptosis markedly in chronic apical periodontitis. A Osteoclast cell growth was suppressed significantly after inhibition of GZMA via crRNA/Cas13d. B Caspase-3 activity was increased obviously after suppression of GZMA via crRNA/Cas13d using ELISA assay. C Apoptosis rate was promoted dramatically after decrease of GZMA via crRNA/Cas13d using flow cytometry. *Means P < 0.05, ** means P < 0.01

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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