Fig. 1

LPS-mediated inflammation. A TeloHAEC viability following LPS exposure. Detection of B LDH, C NO, D VCAM1, E ICAM1, F MCP-1, G IL-1β, and H IL-18 levels. Evaluation of caspase-4 I activity and J levels and K LOX-1 content. Representation of L hsa-miR-15b-5p, M hsa-miR-16-5p, and N hsa-miR-195-5p levels. SIRT4 levels assessed by O ELISA assay and P immunoblotting. M, molecular weight markers; lane 1, Ctr; lane 2, LPS. Mean ± SD, n = 3. *p < 0.05 versus 0 µg/mL or Ctr, ^‡p < 0.01 versus 0 µg/mL or Ctr, ^¶p < 0.001 versus 0 µg/mL or Ctr. Statistical analysis of data was performed using Student’s t-tests