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Fig. 6 | Cellular & Molecular Biology Letters

Fig. 6

From: UGCG modulates heart hypertrophy through B4GalT5-mediated mitochondrial oxidative stress and the ERK signaling pathway

Fig. 6

B4GalT5 was involved in the regulation of myocardial hypertrophy by UGCG. A Masson staining showed the overall degree of myocardial hypertrophy and fibrosis (N = 5). B–E Statistical charts of HW/BW, LW/BW, HW/TL, and LV collagen volume in different groups (N = 5). F, G The representative pictures of the size of the cross-sectional area of cardiomyocytes in the heart and corresponding statistical analysis histogram (N = 5). H–J Representative western blots and statistical analysis histogram reflecting ANP and BNP expressions in hearts (N = 3). K, L HE staining showed the cell surface area of cardiomyocytes from different groups (N = 5). M–O Western blot results of ANP and BNP expression levels in cardiomyocytes from different groups (N = 3). *p < 0.05. AAV-Scramble2: Negative control of AAV-Sh- B4GalT5; Ad-Scramble2: Negative control of Ad-Sh-B4GalT5; B5: B4GalT5

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