Table 1 Correlation between MCCC2 expression and clinicopathological features of CRC patients
Characteristic | MCCC2 | ||
|---|---|---|---|
Low expression (n = 98) | High expression (n = 112) | p-Value | |
Age | 1 | Â | 0.581 |
  < 60 | 54 (55.1) | 57 (50.89) |  |
  ≥ 60 | 44 (44.9) | 55 (49.12) |  |
Gender | Â | Â | 0.018 |
 Female | 34 (34.7) | 58 (51.8) |  |
 Male | 64 (65.3) | 54 (48.2) |  |
Location | Â | Â | 1.000 |
 Colon | 80 (81.6) | 91 (81.2) |  |
 Rectum | 18 (18.4) | 21 (18.8) |  |
Histological grade | Â | Â | 0.028 |
 Well | 23 (23.5) | 19 (17.0) |  |
 Moderately | 49 (50.0) | 76 (67.9) |  |
 Poorly | 26 (26.5) | 17 (15.2) |  |
Depth of invasion | Â | Â | 0.008 |
 T1 | 6 (6.1) | 5 (4.5) |  |
 T2 | 10 (10.2) | 14 (12.5) |  |
 T3 | 41 (41.8) | 24 (21.4) |  |
 T4 | 41 (41.8) | 69 (61.6) |  |
Lymph node metastasis | Â | 0.249 | |
 N0 | 28 (28.6) | 41 (36.6) |  |
 N1 | 46 (46.9) | 53 (47.3) |  |
 N2 | 24 (24.5) | 18 (16.1) |  |
Distant metastasis |  |  |  < 0.001 |
 M0 | 30 (30.6) | 65 (58.0) |  |
 M1 | 68 (69.4) | 47 (42.0) |  |
TNM stage | Â | Â | 0.008 |
 I | 12 (12.2) | 12 (10.7) |  |
 II | 9 (9.2) | 21 (18.8) |  |
 III | 9 (9.2) | 32 (28.6) |  |
 IV | 68 (69.4) | 47 (42.0) |  |
Vein invasion |  |  |  < 0.001 |
 Yes | 20 (20.4) | 21 (18.8) |  |
 No | 78 (79.6) | 91 (81.2) |  |
Nerve invasion | Â | Â | 0.534 |
 Yes | 29 (29.6) | 28 (25.0) |  |
 No | 69 (70.4) | 84 (75.0) |  |
Tumor size | Â | Â | 0.441 |
  ≤ 5 cm | 74 (75.5) | 79 (70.5) |  |
  > 5 cm | 24 (24.5) | 33 (29.5) |  |