Fig. 8From: Irf7 regulates the expression of Srg3 and ferroptosis axis aggravated sepsis-induced acute lung injuryMechanism illustration. Irf7 can activate the expression of Srg3 by transcription, thereby increasing the activity of the NF-κB signaling pathway, activating ferroptosis in lung epithelial cells, promoting M1 macrophage polarization, and exacerbating the symptoms of acute lung injury in sepsisBack to article page