Fig. 11
From: Cadmium promotes nonalcoholic fatty liver disease by inhibiting intercellular mitochondrial transfer
Rho-T1 resistance to cadmium hepatotoxicity and lipid accumulation. Morphological observation of the liver (A). Liver weights (B), Body weights (C), and Liver coefficient (D) in mice treated with Cd (1 mg/kg). Liver function was assessed according to serum levels of ALT (E), AST (F), AST/ALT (G), and ALP (H). Transmission electron microscopy to observe lipid droplets (I). Serum biochemistry to measure the levels of TG (J), TC (K), HDL-C (L), and LDL-C (M). Liver histopathology observed using HE staining (N). Scale bar = 50 μm. Oil red O staining to observe the content of neutral fat in tissues (O). Scale bar = 100 μm. TG, TC, and NEFA levels in the liver were measured (P–R). Levels of CPT1and ACSL1 were determined using western blotting (S). Results are shown as the mean ± SD (n = 3). Compared with the control group, *P < 0.05, **P < 0.01. Compared with the Cd group, #P < 0.05, ##P < 0.01