Fig. 6

Abnormal size and number of LB-like organelles in GCN5L1-KO cells. A Representative images showing Lysotracker-stained organelles in WT, M2, M2 + GCN5L1, and M2 + mito-GCN5L1 cells. B, C The numbers and size (area) in WT, M2, M2 + GCN5L1, and M2 + mito-GCN5L1 cells; **P < 0.01 (Kolmogorov–Smirnov test). D Transmission electron micrographs of WT and M2 cells. Many LB-like organelles are present within the cytoplasm; arrows point to lamellar-like materials in the organelles. E, F The diameters and numbers of LBs in the TEM images were measured and counted with Image J. The results are expressed as the mean ± SD of four independently measured data; *P < 0.05; t-test