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Fig. 5 | Cellular & Molecular Biology Letters

Fig. 5

From: Synthetic CRISPR/dCas9-KRAB system driven by specific PSA promoter suppresses malignant biological behavior of prostate cancer cells through negative feedback inhibition of PSA expression

Fig. 5

PSA promoter-driven CRISPR-dCas9-KRAB promotes the apoptosis of prostate cancer cells. A ELISA experiment results found that PSA-dCas9-KRAB significantly promoted the apoptosis of prostate cancer cells. B Flow cytometry analysis found that PSA-dCas9-KRAB significantly promoted the apoptosis of prostate cancer cells. **P < 0.01 (Student’s t-test, n = 3 replicates)

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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