Fig. 8
From: Astaxanthin alleviates PM2.5-induced cardiomyocyte injury via inhibiting ferroptosis
Astaxanthin attenuates PM2.5-induced ferroptosis in heart. Representative images of fluorescence probe for ROS and its statistical results in heart tissue (A, B). Iron content were detected in the heart tissues (C). Western blots for TfR1, FTL, FTH1, GPX4, and SLC7A11 in heart tissue (D–H). For quantification, protein expression was normalized to GAPDH and the control was set to 1. Values are expressed as mean ± SEM (n = 6). *p < 0.05 difference from the control group; **p < 0.001 difference from the control group; #p < 0.05 difference from the PM2.5 exposure group; and ##p < 0.001 difference from the PM2.5 exposure group