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Fig. 7 | Cellular & Molecular Biology Letters

Fig. 7

From: Transfer RNA-derived small RNA tRF-Glu-CTC attenuates neointimal formation via inhibition of fibromodulin

Fig. 7

tRF-Glu-CTC affected the transcription of FMOD. A The 3′UTR of FMOD, which is predicted to interact with tRF-Glu-CTC, was ligated into the pmiR-RB-Reporter vector. B Dual-luciferase reporter assay performed in the HEK 293 cell line showed that the analogs of tRF-Glu-CTC reduced the relative luciferase activity of the expression vector constructed from wild-type FMOD mRNA and the firefly luciferase gene but did not affect the relative luciferase activity of the expression vector constructed from the mutated FMOD mRNA sequence. n = 3, data are expressed as mean ± standard error, **P < 0.01, ns indicates for not statistically significant

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