Fig. 9

In vivo adipogenic effect of mifepristone in mice. A Summary (n = 8) of the dose-dependent effects of mifepristone (0.1, 1, and 30 mg/kg bw/day) on the time course of changes in the body weight after 12-week oral treatment with mifepristone. The summary of the calculated average daily food consumption during the experimental protocol (8–20 weeks) in the indicated experimental groups. The mice were fed a regular diet (RD) with or without mifepristone for 12 weeks. B Summaries of the body weight-normalized weights of the indicated organs and tissues. C Summaries of the mRNA expression of adiponectin, Fabp4, PPARγ and PPARγ2 in epididymal adipose tissues obtained from the mice of the indicated experimental groups. The mRNA levels were normalized by that of 18S rRNA and expressed as a fold increase from those of the mice of RD. The data represent the mean ± S.E.M. *P < 0.05; **P < 0.01 vs. RD