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Fig. 1 | Cellular & Molecular Biology Letters

Fig. 1

From: Sialylation on vesicular integrin β1 determined endocytic entry of small extracellular vesicles into recipient cells

Fig. 1

Enriched sialylation on sEV of bladder cancer cells and serums. A YTS-1 sEV morphology (TEM image). B The particle size of YTS-1 sEV, determined by nanoparticle tracking analysis (NTA). C Expression of sEV markers, analyzed by western blotting. D Sialic acid levels in YTS-1 cells lysate and YTS-1 sEV. Coomassie Brilliant Blue (CBB). E Sialic acid levels on sEV from YTS-1, T24, KK47 and HCV29 cells by ELISA. F–H Proliferation (F), migratory ability (G), apoptosis (H) of HCV29 treated with YTS-1 sEV. I Sialylation of plasma from bladder cancer patients and healthy subjects by ELISA. BC: bladder cancer patients. HS: healthy subjects. J Sialylation of plasma sEV by ELISA. K Bladder cancer ROC curve based on plasma sialylation. AUC: area under the curve. L Bladder cancer ROC curve based on plasma sEV sialylation. M Levels of sialylated CD63 in plasma detected by ELISA. N Levels of total CD63 in plasma detected by ELISA

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Cellular & Molecular Biology Letters

ISSN: 1689-1392

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