Fig. 1

Western blots and relative densitometries of AGC1 and AGC2 in Oli-Neu cells (a, b). GAPDH was used as control and for endogenous normalization. Values are mean ± standard error of the mean (s.e.m.) of at least three independent experiments; ***p < 0.001, **p < 0.01, *p < 0.05, compared with control Oli-Neu; Student’s t-test. Principal component analysis (PCA) of control and kdAGC1 samples gene expression data based on rlog-normalized reads values (c). SLC25A12 (AGC1) and SLC25A13 (AGC2) expression values [transcripts per million (TPMs)] with respective fold changes and significance levels (d, e)