Table 1 The roles of autophagy associated-circRNAs in chemo- and radio-therapy of malignant tumors

GBM

circLIFR↓

hsa_circ_0072309

LIFR

miR-100

p53↑

Promotion

TMZ sensitivity

[137]

CRC

circBANP↑

hsa_circ_0003098

BANP

miR-338-3p

/

Promotion

Radioresistance

[20]

GC

circCPM↑

hsa_circ_0027497

CPM

miR-21-3p

PRKAA2↑

Promotion

5-FU resistance

[19]

circCUL2↓

hsa_circ_0000234

CUL2

miR-142-3p

ROCK2↑

Inhibition

DDP sensitivity

[145]

circPVT1↑

/

PVT1

miR-30a-5p

YAP1↑

Promotion

DDP resistance

[147]

circMCTP2↓

hsa_circ_0000657

MCTP2

miR-99a-5p

MTMR3↑

Inhibition

DDP sensitivity

[149]

RC

circCCNB2↑

hsa_circ_0035483

CCNB2

miR-335

cyclin B1↑

Promotion

GEM resistance

[150]

TC

circEIF6↑

hsa_circ_0060060

EIF6

miR-144-3p

TGF-α↑

Promotion

DDP resistance

[154]

BC

circABCB10↑

hsa_circ_0008717

ABCB10

let-7a-5p

DUSP7↑

Promotion

PTX resistance

[155]

circ_0006528↑

hsa_circ_0006528

PRELID2

miR-1299

CDK8↑

Promotion

PTX resistance

[156]

circAKT3↑

hsa_circ_0000199

AKT3

miR-613/miR-206

PI3K/AKT/mTOR pathway↑

Inhibition

ADR/DDP/PTX/GEM resistance

[157]

circINTS4↑

hsa_circ_0002476

INTS4

miR-129-5p

POM121↑

Promotion

ADR resistance

[158]

NSCLC

circPABPC1↑

hsa_circ_0085131

PABPC1

miR-654-5p

ATG7↑

Promotion

DDP resistance

[170]

circRNA_100565↑

hsa_circ_0017956

MLLT10

miR-337-3p

DAM28↑

Promotion

DDP resistance

[172]

CC

circRNF121↑

hsa_circ_0023404

RNF121

miR-5047

/

Inhibition

DDP resistance

[176]

circMTO1↑

hsa_circ_0007874

MTO1

miR-6893

/

Promotion

DDP resistance

[180]

Laryngocarcinoma

circPGAM1↑

/

PGAM1

miR-376a

ATG2A↑

Promotion

DDP resistance

[182]

circPARD3↑

circ_00043

PARD3

miR-145-5p

PRKCI↑

Inhibition

DDP resistance

[184]

OSCC

circPKD2↓

hsa_circ_0070401

PKD2

miR‐204‐3p

ATG13↑

Promotion

DDP sensitivity

[186]

PC

circCCNB2↑

hsa_circ_0035483

CCNB2

miR-30b-5p

KIF18A↑

Promotion

Radioresistance

[191]