Fig. 3
From: miR-29b-3p regulates cardiomyocytes pyroptosis in CVB3-induced myocarditis through targeting DNMT3A
MiR-29b-3p was significantly upregulated in VMC models. The total RNA, extracted from VMC mice and the control, was applied to transcriptome sequencing (N = 3). A Compared with the control group, there were 1444 miRNAs increased and 1138 miRNAs decreased in VMC mice heart tissues. B The most differentially expressed miRNAs were displayed through clustering heat map. C The Venn diagram indicated that five miRNAs have consistent expression trends in all samples. D The expression levels of miR-29b-3p in HL-1 cells, primary cardiomyocytes, and heart tissue were evaluated by qRT–PCR. N = 3, **p < 0.01, ***p < 0.001, and ****p < 0.0001